Non-Obstructive Azoospermia with Hypergonadotropic Hypogonadism without a Significant Abnormalities in the Physical Examination

Background: Around 10 % of infertile men and 1 percent all males have azoospermia. There are two types azoospermia, which obstructive non-obstructive Non-obstructive azoospermia's main mechanism is because the testes fail to produce sex hormone induce spermatogenesis (primary testicular failure).
 Case: A patient 28 years old has a job as car paint worker. He came with chief complaint infertility since half ago. his wife were having intercourse 3-4 times week. Past medical history unremarkable. His wife’s also Physical examination ultrasound normal. The semen analysis in this was azoospermia for 2 different span weeks no abnormalities accessory gland. Hormonal profiles results testosterone level 2,32 ng/mL FSH 15,03 mIU/mL, indicatehypergonadotropic hypogonadism. suggested evaluate further (complete hormonal profile, karyotyping analysis, Y-Chromosome microdeletion) educate about possibility conceive assisted reproductive technology (ART).
 Discussion: Hypergonadotropic hypogonadism challenging case that needs complete assessment such Y-chromosome microdeletion also, case, thinner exposure workplace needed be considered. chance normal conception very small, procedure necessary.
 Conclusion: Some usually present physical patients. This convinces us importance thorough taking other investigations. Managing will challenging, goal therapy achieve able use spermatozoa available ICSI.